DRUG
simvastatin
Hypercholesterolemia (FDA 1991)
2 hypotheses across 2 therapeutic domains
ALL HYPOTHESES
Repurposing candidates for simvastatin
Pancreatic cancer 1
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| mevalonate pathway | ferroptosis | 0.208 | Mid | reproduces known | none |
Rheumatoid arthritis 1
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| Alb | rheumatoid arthritis | 0.208 | Mid | reproduces known | completed |