Applications

Robertium's cross-domain methodology, applied to specific therapeutic areas

The full catalog at /hypotheses lists every cross-domain hypothesis Robertium has surfaced. These application pages narrow the view to one therapeutic area at a time, so a researcher working on a specific disease can see what candidates exist for their domain without scanning the whole catalog.

Application area

Oncology

Pancreatic ductal adenocarcinoma (PDAC) · Glioblastoma multiforme (GBM)

Two cancers with limited treatment options and high unmet need. Robertium surfaces drug candidates from other therapeutic literatures that share molecular mediators with these tumors — including KRAS, EGFR, mTOR, and PKM2.

877 hypotheses View applications →

Application area

Neurology & psychiatry

Alzheimer's · ALS · Epilepsy · Depression

Four neurological and psychiatric conditions that share substantial mechanistic overlap — neuroinflammation, protein aggregation, neurotransmitter imbalance, neuronal excitability. Rich substrate for cross-domain repurposing analysis.

1,143 hypotheses View applications →

More areas coming

Additional application pages will be added as the corpus expands to cover new therapeutic domains. The methodology — Swanson ABC discovery across a shared knowledge graph — is the same for every area; what differs is which diseases are represented in the literature corpus.

For the complete cross-domain catalog across every domain Robertium currently indexes, see /hypotheses. For the underlying methodology, see /method.