DRUG

gemcitabine

5 hypotheses across 2 therapeutic domains

ALL HYPOTHESES

Repurposing candidates for gemcitabine

Depression 4

Mediator Outcome Score Tier Lit. status Trial
IL-8 major depressive disorder 0.271 High novel signal none
IL-8 depressed mood 0.220 Mid partial evidence none
IL-8 response to ketamine 0.220 Mid novel signal none
IL-8 depression severity 0.220 Mid novel signal none

Rheumatoid arthritis 1

Mediator Outcome Score Tier Lit. status Trial
STAT3 prurigo nodularis 0.208 Mid partial evidence none

Clinical trials

200 registered trials for gemcitabine

Source: ClinicalTrials.gov