ALL HYPOTHESES
Repurposing candidates for linagliptin
Alzheimer 1
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| SIRT1 | Alzheimer's disease | 0.208 | Mid | reproduces known | completed |
Inflammatory bowel disease 3
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| DPP-4 | disease activity | 0.358 | High | partial evidence | completed | |
| DPP-4 | biological treatment response | 0.318 | High | novel signal | none | |
| DPP-4 | treatment escalation | 0.318 | High | partial evidence | none |