DRUG

Ketogenic diet

Refractory pediatric epilepsy

7 hypotheses across 2 therapeutic domains

ALL HYPOTHESES

Repurposing candidates for Ketogenic diet

ALS 4

Mediator Outcome Score Tier Lit. status Trial
Sod1 ALS 0.383 High reproduces known active Case study →
Sod1 familial amyotrophic lateral sclerosis 0.248 Mid novel signal none
Sod1 familial ALS 0.230 Mid partial evidence none
Kynurenine ALS 0.220 Mid reproduces known active

Alzheimer 3

Mediator Outcome Score Tier Lit. status Trial
GFAP Alzheimer disease 0.208 Mid reproduces known active
GFAP cognitive decline 0.208 Mid reproduces known active
GFAP cognitive impairment 0.208 Mid reproduces known active

Clinical trials

200 registered trials for Ketogenic diet

Source: ClinicalTrials.gov

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