DRUG
carbamazepine
Epilepsy, trigeminal neuralgia, bipolar disorder
3 hypotheses across 2 therapeutic domains
ALL HYPOTHESES
Repurposing candidates for carbamazepine
ALS 1
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| Cx43 | ALS | 0.248 | Mid | partial evidence | none |
Pancreatic cancer 2
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| KRAS | pancreatic ductal adenocarcinoma | 0.300 | High | novel signal | none | Case study → |
| KRAS | pancreatic cancer | 0.264 | Mid | partial evidence | none |