ALL HYPOTHESES
Repurposing candidates for amantadine
ALS 2
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| NMDA receptor | pain | 0.269 | Mid | reproduces known | active | |
| NMDA receptor | cell-autonomous excitotoxicity | 0.269 | Mid | novel signal | none |
Epilepsy 2
| Mediator | Outcome | Score | Tier | Lit. status | Trial | |
|---|---|---|---|---|---|---|
| NMDA receptor | neurodevelopmental disorders | 0.269 | Mid | partial evidence | completed | |
| NMDA receptor | neuronal death | 0.269 | Mid | partial evidence | none |