Discovery dashboard

What's new in drug repurposing this week

Live signals from 1,618 hypotheses tracked since 2026-05-12. 14 have reached strong support, 61 have partial support, 138 new PubMed citations recorded.

Last refresh: 2026-05-13

Hypotheses gaining literature support

New PubMed citations matching the drug × outcome pair since the 2026-05-12 snapshot. Strong support = 3+ new PMIDs or any phase-2+ trial; partial = 1-2 new PMIDs.

  1. #1
    resveratrol PGC1α inflammation
    Strong support +13 new PMIDs mid quality score 0.208 ALS → Inflammatory bowel disease
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  2. #2
    resveratrol SIRT1 inflammation
    Strong support +13 new PMIDs mid quality score 0.208 ALS → Type 2 diabetes
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  3. #3
    metformin DR5 apoptosis
    Strong support +6 new PMIDs mid quality score 0.208 Pancreatic cancer → Glioblastoma
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  4. #4
    pembrolizumab PD-1 prognosis
    Strong support +4 new PMIDs mid quality score 0.230 Multiple sclerosis → Pancreatic cancer
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  5. #5
    resveratrol SIRT1 proliferation
    Strong support +3 new PMIDs high quality score 0.373 Type 2 diabetes → Pancreatic cancer
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Strong-support cohort

The full 14-hypothesis short list that crossed the strong-support threshold. What does this mean? A tracked hypothesis transitions to strong support when at least 3 new PubMed citations match the drug × outcome pair since the snapshot, or any phase-2+ clinical trial is registered. Partial = 1-2 new citations.

Drugs with the most active recruiting trials

Cross-referenced with the Robertium catalog: drugs that are actively recruiting patients and have novel cross-domain hypotheses are the highest-priority candidates for outreach.

  1. #1
    SGLT2i
    61 recruiting 200 total trials 1 hypothesis
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  2. #2
    tACS
    58 recruiting 200 total trials 1 hypothesis
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  3. #3
    osimertinib
    57 recruiting 200 total trials 11 hypotheses
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  4. #4
    upadacitinib
    53 recruiting 163 total trials 1 hypothesis
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  5. #5
    Ruxolitinib
    50 recruiting 200 total trials 1 hypothesis
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