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Source papers, claims, scoring, and embedding config are recovered; generation-time metadata (exact git commit at gen time, host, exact command) is not recoverable.","source_papers":[{"doi":"10.1016/j.freeradbiomed.2022.08.012","pmid":"35964840","year":2022,"roles":["mediator_outcome"],"title":"Pros and cons of NRF2 activation as adjunctive therapy in rheumatoid arthritis","journal":"Free Radic Biol Med","work_id":290626,"publication_date":"2022-08-11"},{"doi":"10.3390/ijms23126773","pmid":"35743211","year":2022,"roles":["drug_mediator"],"title":"Mechanisms of Sensitivity and Resistance of Primary Effusion Lymphoma to Dimethyl Fumarate (DMF)","journal":"Int J Mol Sci","work_id":205079,"publication_date":"2022-06-17"},{"doi":"10.1007/s13311-020-00855-0","pmid":"32394330","year":2020,"roles":["drug_mediator"],"title":"Characterization of More Selective Central Nervous System Nrf2-Activating Novel Vinyl Sulfoximine Compounds Compared to Dimethyl Fumarate","journal":"Neurotherapeutics","work_id":204231,"publication_date":"2020-05-11"},{"doi":"10.1111/febs.15485","pmid":"32672401","year":2020,"roles":["drug_mediator"],"title":"Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1","journal":"FEBS J","work_id":196503,"publication_date":"2020-07-16"},{"doi":"10.1016/j.jphs.2018.06.008","pmid":"30042024","year":2018,"roles":["drug_mediator"],"title":"Dimethyl fumarate ameliorates chemotherapy agent-induced neurotoxicity in vitro","journal":"J Pharmacol Sci","work_id":198907,"publication_date":"2018-06-01"}],"source_paper_count":5,"extracted_claims":[{"side":"drug_mediator","object":"Nrf2","context":"in cellular context","subject":"DMF","work_id":196503,"claim_id":141353,"polarity":"positive","predicate":"activates","confidence":0.7,"extraction_run_id":25},{"side":"drug_mediator","object":"Nrf2","context":"in PC12 cells","subject":"DMF","work_id":198907,"claim_id":145742,"polarity":"positive","predicate":"activates","confidence":0.95,"extraction_run_id":25},{"side":"drug_mediator","object":"Nrf2","context":"in vitro and in vivo","subject":"DMF","work_id":204231,"claim_id":153533,"polarity":"positive","predicate":"activates","confidence":0.9,"extraction_run_id":25},{"side":"drug_mediator","object":"NRF2","context":"in PEL cells","subject":"DMF","work_id":205079,"claim_id":154674,"polarity":"positive","predicate":"activates","confidence":0.9,"extraction_run_id":25},{"side":"mediator_outcome","object":"toxicity of conventional anti-rheumatic therapies","context":"in rheumatoid arthritis treatment","subject":"NRF2","work_id":290626,"claim_id":222757,"polarity":"positive","predicate":"decreases","confidence":0.7,"extraction_run_id":29}],"extracted_claim_count":5,"extraction":{"model":"deepseek-v4-flash","model_source":"configured","prompt_version":"v1_2026_05_07","run_ids":[25,29]},"bridge":{"a_to_b_predicate":"activates","b_to_c_predicate":"decreases","a_to_b_evidence_count":4,"b_to_c_evidence_count":1,"edge_support_log_ab":1.6094379124341003,"edge_support_log_bc":0.6931471805599453,"novelty_factor":1.0,"direct_a_to_c_count":0},"embedding":{"model":"bge-m3","dim":1024,"max_length":8192,"similarity_scores":{}},"scoring":{"method":"swanson_abc_log_evidence_with_novelty_penalty","formula":"score = min((log(ab+1) + log(bc+1)) * novelty / 10, 1.0); novelty = 1.0 if direct==0 else 0.7 / (direct+1)","score_raw":0.23025850929940456,"score":0.23025850929940456,"quality_tier":"mid","quality_reason":null},"pipeline_run":{"id":4,"run_uuid":"eb8b7730-d92e-4cd5-95dd-95f6c5d62cc2","command":"scripts/backfill_provenance_v2.py:v2_2026_05_12","status":"completed","git_commit":"9996ffaa56e9b7cd5f677bd8203624c2c18aa000","host":"MacBook-Pro-Daniel96.local","started_at":"2026-05-12T21:35:53.363326+00:00","ended_at":"2026-05-12T21:43:41.903387+00:00","notes":"Retroactive provenance backfill on 2026-05-13 for snapshot v2_2026_05_12. Synthetic pipeline_runs row — original generation run records are lost (pre-date provenance schema). All recoverable fields populated from current DB state (claims, works, repurposing_hypotheses); pipeline_run record is synthetic, hence completeness='partial_backfill'.\nBackfilled 1,618 provenance rows. Source papers: avg=3.73, zero=0. Claims matched: avg=4.09, zero=0.\nRefreshed 1,618 provenance rows. Source papers: avg=3.73, zero=0. Claims matched: avg=4.09, zero=0.\nRefreshed 1,618 provenance rows. Source papers: avg=3.73, zero=0. Claims matched: avg=4.09, zero=0.","domains":["als","alzheimer","depression","epilepsy","glioblastoma","inflammatory_bowel_disease","multiple_sclerosis","pancreatic_cancer","rheumatoid_arthritis","type_2_diabetes"]},"generated_at":"2026-05-12T21:43:40.945575+00:00"}