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Source papers, claims, scoring, and embedding config are recovered; generation-time metadata (exact git commit at gen time, host, exact command) is not recoverable.","source_papers":[{"doi":"10.3390/antiox13070795","pmid":"39061864","year":2024,"roles":["drug_mediator"],"title":"Hydroethanolic Extract of Lepidium apetalum Willdenow Alleviates Dextran Sulfate Sodium-Induced Colitis by Enhancing Intestinal Barrier Integrity and Inhibiting Oxidative Stress and Inflammasome Activation","journal":"Antioxidants (Basel)","work_id":277394,"publication_date":"2024-06-29"},{"doi":"10.1159/000525091","pmid":"35576897","year":2022,"roles":["mediator_outcome"],"title":"Genetic Epidemiology of Amyotrophic Lateral Sclerosis in Norway: A 2-Year Population-Based Study","journal":"Neuroepidemiology","work_id":52596,"publication_date":"2022-01-01"},{"doi":"10.1002/jcb.29048","pmid":"31134679","year":2019,"roles":["mediator_outcome"],"title":"SOD1 in amyotrophic lateral sclerosis development – in silico analysis and molecular dynamics of A4F and A4V variants","journal":"J Cell Biochem","work_id":135426,"publication_date":"2019-05-27"},{"doi":"10.1080/21678421.2018.1457057","pmid":"29609497","year":2018,"roles":["mediator_outcome"],"title":"A novel D90_K91insN mutation in exon 4 of the <i>SOD1</i> gene caused familial amyotrophic lateral sclerosis in a Chinese pedigree","journal":"Amyotroph Lateral Scler Frontotemporal Degener","work_id":138878,"publication_date":"2018-04-02"},{"doi":"10.1080/07391102.2017.1407675","pmid":"29157189","year":2017,"roles":["mediator_outcome"],"title":"Molecular dynamics of a far positioned SOD1 mutant V14M reveals pathogenic misfolding behavior","journal":"J Biomol Struct Dyn","work_id":52816,"publication_date":"2017-11-21"},{"doi":"10.3109/21678421.2015.1111906","pmid":"26630559","year":2015,"roles":["mediator_outcome"],"title":"Identification of L84F mutation with a novel nucleotide change c.255G &gt; T in the superoxide dismutase gene in a North Indian family with amyotrophic lateral sclerosis","journal":"Amyotroph Lateral Scler Frontotemporal Degener","work_id":131884,"publication_date":"2015-12-02"}],"source_paper_count":6,"extracted_claims":[{"side":"drug_mediator","object":"SOD1","context":"DSS-induced colitis mice","subject":"LWE","work_id":277394,"claim_id":250901,"polarity":"positive","predicate":"upregulates","confidence":0.95,"extraction_run_id":31},{"side":"mediator_outcome","object":"familial amyotrophic lateral sclerosis","context":"in Norwegian ALS patients","subject":"SOD1","work_id":52596,"claim_id":32940,"polarity":"positive","predicate":"associated_with","confidence":0.75,"extraction_run_id":15},{"side":"mediator_outcome","object":"familial amyotrophic lateral sclerosis","context":"in humans","subject":"SOD1","work_id":52816,"claim_id":33305,"polarity":"positive","predicate":"causes","confidence":0.9,"extraction_run_id":15},{"side":"mediator_outcome","object":"familial amyotrophic lateral sclerosis","context":"North Indian family","subject":"SOD1","work_id":131884,"claim_id":97967,"polarity":"positive","predicate":"associated_with","confidence":0.95,"extraction_run_id":21},{"side":"mediator_outcome","object":"familial amyotrophic lateral sclerosis","context":"in silico analysis of A4F and A4V variants","subject":"SOD1","work_id":135426,"claim_id":98773,"polarity":"positive","predicate":"associated_with","confidence":0.9,"extraction_run_id":21},{"side":"mediator_outcome","object":"familial amyotrophic lateral sclerosis","context":"Chinese pedigree with autosomal dominant inheritance and reduced penetrance","subject":"SOD1","work_id":138878,"claim_id":101174,"polarity":"positive","predicate":"causes","confidence":0.95,"extraction_run_id":21}],"extracted_claim_count":6,"extraction":{"model":"deepseek-v4-flash","model_source":"configured","prompt_version":"v1_2026_05_07","run_ids":[15,21,31]},"bridge":{"a_to_b_predicate":"upregulates","b_to_c_predicate":"associated_with","a_to_b_evidence_count":1,"b_to_c_evidence_count":5,"edge_support_log_ab":0.6931471805599453,"edge_support_log_bc":1.791759469228055,"novelty_factor":1.0,"direct_a_to_c_count":0},"embedding":{"model":"bge-m3","dim":1024,"max_length":8192,"similarity_scores":{}},"scoring":{"method":"swanson_abc_log_evidence_with_novelty_penalty","formula":"score = min((log(ab+1) + log(bc+1)) * novelty / 10, 1.0); novelty = 1.0 if direct==0 else 0.7 / (direct+1)","score_raw":0.24849066497880004,"score":0.24849066497880004,"quality_tier":"mid","quality_reason":null},"pipeline_run":{"id":4,"run_uuid":"eb8b7730-d92e-4cd5-95dd-95f6c5d62cc2","command":"scripts/backfill_provenance_v2.py:v2_2026_05_12","status":"completed","git_commit":"9996ffaa56e9b7cd5f677bd8203624c2c18aa000","host":"MacBook-Pro-Daniel96.local","started_at":"2026-05-12T21:35:53.363326+00:00","ended_at":"2026-05-12T21:43:41.903387+00:00","notes":"Retroactive provenance backfill on 2026-05-13 for snapshot v2_2026_05_12. Synthetic pipeline_runs row — original generation run records are lost (pre-date provenance schema). All recoverable fields populated from current DB state (claims, works, repurposing_hypotheses); pipeline_run record is synthetic, hence completeness='partial_backfill'.\nBackfilled 1,618 provenance rows. Source papers: avg=3.73, zero=0. Claims matched: avg=4.09, zero=0.\nRefreshed 1,618 provenance rows. Source papers: avg=3.73, zero=0. Claims matched: avg=4.09, zero=0.\nRefreshed 1,618 provenance rows. Source papers: avg=3.73, zero=0. Claims matched: avg=4.09, zero=0.","domains":["als","alzheimer","depression","epilepsy","glioblastoma","inflammatory_bowel_disease","multiple_sclerosis","pancreatic_cancer","rheumatoid_arthritis","type_2_diabetes"]},"generated_at":"2026-05-12T21:43:40.945575+00:00"}